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Pantoprazole & Domperidone Tablets

Pantoprazole & Domperidone Tablets
Pantoprazole & Domperidone Tablets
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Product Code : MEDZOLE-D
Brand Name : MEDZOLE-D
Price And Quantity
  • Minimum Order Quantity
  • 500
  • Unit of Measure
  • Box/Boxes
  • Price
  • 110.00 INR
  • Price Range
  • 1.00 - 1.00 INR
Product Specifications
  • Ingredients
  • Domperidone Pantoprazole Capsule - Composition and Active Ingredients Domperidone Pantoprazole Capsule is composed of the following active ingredients (salts) Domperidone - 30MG Pantoprazole - 40MG Please note that this medicine may be available in various strengths for each active ingredient listed above.
  • Sub Ingredients
  • Domperidone Pantoprazole Capsule - Composition and Active Ingredients Domperidone Pantoprazole Capsule is composed of the following active ingredients (salts) Domperidone - 30MG Pantoprazole - 40MG Please note that this medicine may be available in various strengths for each active ingredient listed above.
  • Physical Form
  • Tablets
  • Function
  • Treat Gastric Issues
  • Dosage Guidelines
  • With Water
  • Dosage
  • AS DIRECTED BY THE PHYSICIAN
  • Dosage Form
  • Capsul
  • Quantity
  • 500 Boxes
  • Storage Instructions
  • Below 25/C. Protect form light.
Product Description


Pantoprazole & Domperidone Tablets are proton pump inhibitor that reductions the measure of corrosive delivered in the stomach. These are utilized to treat erosive esophagitis (harm to the throat from stomach corrosive caused by gastroesophageal reflux malady, or GERD) in grown-ups and kids who are no less than 5 years of age. In addition, Pantoprazole & Domperidone Tablets are generally surrendered for over two months on end while your throat recuperates. These are likewise deployed to treat Zollinger-Ellison disorder and different conditions including abundance stomach acid.
What is pantoprazole?

Pantoprazole is a proton pump inhibitor that decreases the amount of acid produced in the stomach.

Pantoprazole is used to treat erosive esophagitis (damage to the esophagus from stomach acid caused bygastroesophageal reflux disease, or GERD) in adults and children who are at least 5 years old. Pantoprazole is usually given for up to 8 weeks at a time while your esophagus heals.

Pantoprazole is also used to treat Zollinger-Ellison syndrome and other conditions involving excess stomach acid.
Important Information

Pantoprazole is not for the immediate relief of heartburn symptoms.

Call your doctor at once if you have symptoms of a serious side effect: decreased urination, blood in your urine, severe stomach pain, watery or bloody diarrhea, or symptoms ofjoint pain or a skin rash that worsens in sunlight.

You may be more likely to have a broken bone while using pantoprazole. Tell your doctor right away if you have unusual pain in your wrist, hip, or spine.

Heartburn is often confused with the first symptoms of a heart attack. Seek emergency medical attention if you have chest pain or heavy feeling, pain spreading to the arm or shoulder, nausea, sweating, and a general ill feeling.

Long-term treatment with pantoprazole may also make it harder for your body to absorb vitamin B-12, resulting in a deficiency of this vitamin. Talk with your doctor if you need long-term pantoprazole treatment and you have concerns about vitamin B-12 deficiency.
Before taking this medicine

Heartburn can mimic the first symptoms of a heart attack. Get emergency medical help if you have chest pain that spreads to your jaw or shoulder and you feel anxious or light-headed.

You should not use this medicine if:

    you also take medicine that contains rilpivirine (Edurant, Complera, Juluca, Odefsey); or

    you are allergic to pantoprazole or similar medicines (lansoprazole, omeprazole, Nexium,Prevacid, Prilosec, and others).

Tell your doctor if you have ever had:

    low levels of magnesium in your blood;

    lupus; or

    osteoporosis or low bone mineral density.

You may be more likely to have a broken bone while using pantoprazole. Talk with your doctor about ways to keep your bones healthy, especially if you are an adult over 50.

It is not known whether this medicine will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.

You should not breast-feed while using this medicine.

Pantoprazole is not approved for use by anyone younger than 5 years old.
How should I use pantoprazole?

Take pantoprazole exactly as prescribed by your doctor. Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.

Use the lowest dose for the shortest amount of time needed to treat your condition.

Pantoprazole is taken by mouth (oral) or given as an infusion into a vein (injection). A healthcare provider may teach you how to properly use the injection by yourself.

Pantoprazole tablets are taken by mouth, with or without food. The oral granules should be taken 30 minutes before a meal.

Do not crush, chew, or break the tablet. Swallow it whole.

The oral granules should be mixed with applesauce or apple juice and given either by mouth or through a nasogastric (NG) tube.

Read and carefully follow any Instructions for Use provided with your medicine. Ask your doctor or pharmacist if you have any questions.

Use this medicine for the full prescribed length of time. Your symptoms may improve before the condition is fully treated.

If you use pantoprazole for longer than 3 years, you could develop a vitamin B-12 deficiency. Talk to your doctor about how to manage this condition.

Call your doctor if your symptoms do not improve or if they get worse while you are using this medicine.

Pantoprazole can cause false results with certain medical tests, including a urine drug screening test. Tell the doctor or laboratory staff that you are using this medicine.

Store this medicine at room temperature away from moisture, heat, and light.
Pantoprazole dosing information

Usual Adult Dose for Erosive Esophagitis:

Treatment of Erosive Esophagitis:
40 mg orally once a day for up to 8 weeks; however an additional 8 weeks may be considered for patients who have not healed after the initial treatment. Safety and efficacy beyond 16 weeks of therapy have not been established.

Maintenance of Healing of Erosive Esophagitis:
40 mg orally once a day. Controlled studies have been limited to 12 months of pantoprazole therapy.

Usual Adult Dose for Gastroesophageal Reflux Disease:

Parenteral: 40 mg once a day for 7 to 10 days, administered via intravenous infusion over a period of 15 minutes. Intravenous therapy should be discontinued as soon as the patient is able to resume oral therapy.

Oral: 40 mg orally once a day, for short-term administration (up to 8 weeks); however an additional 8 weeks may be considered for patients who have not healed after the initial treatment. Safety and efficacy beyond 16 weeks of therapy have not been established.

Usual Adult Dose for Duodenal Ulcer:

Study (n=54)
40 mg orally once a day, dose was increased every 12 weeks by 40 mg increments to a maximum of 120 mg per day, for 28 weeks. Data have revealed that monotherapy with daily doses of 40 mg have been associated with complete duodenal ulcer healing in up to 87% and 94% of patients after 4 weeks and 8 weeks respectively.

Usual Adult Dose for Gastric Ulcer:

40 mg orally once a day. Data have revealed that monotherapy with daily doses of 40 mg have been associated with complete gastric ulcer healing in up to 87% and 97% of patients after 4 weeks and 8 weeks respectively.

You should not breast-feed while using this medicine.

Pantoprazole is not approved for use by anyone younger than 5 years old.
How should I use pantoprazole?

Take pantoprazole exactly as prescribed by your doctor. Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.

Use the lowest dose for the shortest amount of time needed to treat your condition.

Pantoprazole is taken by mouth (oral) or given as an infusion into a vein (injection). A healthcare provider may teach you how to properly use the injection by yourself.

Pantoprazole tablets are taken by mouth, with or without food. The oral granules should be taken 30 minutes before a meal.

Do not crush, chew, or break the tablet. Swallow it whole.

The oral granules should be mixed with applesauce or apple juice and given either by mouth or through a nasogastric (NG) tube.

Read and carefully follow any Instructions for Use provided with your medicine. Ask your doctor or pharmacist if you have any questions.

Use this medicine for the full prescribed length of time. Your symptoms may improve before the condition is fully treated.

If you use pantoprazole for longer than 3 years, you could develop a vitamin B-12 deficiency. Talk to your doctor about how to manage this condition.

Call your doctor if your symptoms do not improve or if they get worse while you are using this medicine.

Pantoprazole can cause false results with certain medical tests, including a urine drug screening test. Tell the doctor or laboratory staff that you are using this medicine.

Store this medicine at room temperature away from moisture, heat, and light.
Pantoprazole dosing information

Usual Adult Dose for Erosive Esophagitis:

Treatment of Erosive Esophagitis:
40 mg orally once a day for up to 8 weeks; however an additional 8 weeks may be considered for patients who have not healed after the initial treatment. Safety and efficacy beyond 16 weeks of therapy have not been established.

Maintenance of Healing of Erosive Esophagitis:
40 mg orally once a day. Controlled studies have been limited to 12 months of pantoprazole therapy.

Usual Adult Dose for Gastroesophageal Reflux Disease:

Parenteral: 40 mg once a day for 7 to 10 days, administered via intravenous infusion over a period of 15 minutes. Intravenous therapy should be discontinued as soon as the patient is able to resume oral therapy.

Oral: 40 mg orally once a day, for short-term administration (up to 8 weeks); however an additional 8 weeks may be considered for patients who have not healed after the initial treatment. Safety and efficacy beyond 16 weeks of therapy have not been established.

Usual Adult Dose for Duodenal Ulcer:

Study (n=54)
40 mg orally once a day, dose was increased every 12 weeks by 40 mg increments to a maximum of 120 mg per day, for 28 weeks. Data have revealed that monotherapy with daily doses of 40 mg have been associated with complete duodenal ulcer healing in up to 87% and 94% of patients after 4 weeks and 8 weeks respectively.

Usual Adult Dose for Gastric Ulcer:


40 mg orally once a day. Data have revealed that monotherapy with daily doses of 40 mg have been associated with complete gastric ulcer healing in up to 87% and 97% of patients after 4 weeks and 8 weeks respectively.
Usual Adult Dose for Zollinger-Ellison Syndrome

Oral: 40 mg orally 2 times a day
-Maximum dose: 240 mg/day

Parenteral:
  • -Initial dose: 80 mg IV every 12 hours, given over at least 2 minutes OR over 15 minutes
  • -Maintenance dose: 80 mg IV every 8 to 12 hours, given over at least 2 minutes OR over 15 minutes
  • -Maximum dose: 240 mg/day
  • -Maximum duration of therapy: 6 days
Comments:
  • -IV treatment should be discontinued once the patient is able to take an oral formulation.
  • -Use of the IV formulation for longer than 6 days and/or with doses higher than 240 mg has not been adequately studied.
  • -Patients may be vulnerable to increased acid production despite a short period of loss of effective inhibition.
  • -Patients given the oral formulation should be continued on therapy for as long as clinically necessary.
Use: Treatment of pathological hypersecretory conditions, including Zollinger-Ellison syndrome
Usual Pediatric Dose for Erosive Esophagitis

5 years and older:
  • 15 to less than 40 kg: 20 mg orally once a day
  • 40 kg and greater: 40 mg orally once a day
  • Duration of therapy: Up to 8 weeks
Comment: Safety has not been established in treatment beyond 8 weeks.

Uses:
  • -Short-term treatment in the healing and symptomatic relief of erosive esophagitis
  • -Short-term treatment of GERD in patients with a history of erosive esophagitis
  • Usual Pediatric Dose for Gastroesophageal Reflux Disease
5 years and older:
  • 15 to less than 40 kg: 20 mg orally once a day
  • 40 kg and greater: 40 mg orally once a day
  • Duration of therapy: Up to 8 weeks
Comment: Safety has not been established in treatment beyond 8 weeks.

Uses:
  • -Short-term treatment in the healing and symptomatic relief of erosive esophagitis
  • -Short-term treatment of GERD in patients with a history of erosive esophagitis
  • Renal Dose Adjustments
No adjustment recommended.
  • Liver Dose Adjustments
  • Doses over 40 mg/day have not been studied in patients with liver impairment.
  • Precautions
  • Safety and efficacy of oral formulations have not been established in patients younger than 5 years. The IV formulation is not recommended for use in children.
  • Consult WARNINGS section for additional precautions.
Other Comments

Administration advice:

  • -Tablet formulations should be swallowed whole, without crushing/chewing; tablets may be taken with or without food.
  • -For patients unable to swallow a 40 mg tablet, two 20 mg tablets may be taken.
  • -Oral suspension/granule formulations should be taken on an empty stomach, preferably 30 to 60 minutes before a meal. The 40 mg packet should not be divided to create 20 mg dosages.
  • -The granule formulation may be sprinkled into applesauce or mixed into a small volume of either apple juice or orange juice and swallowed immediately. This drug may be mixed with apple juice and administered via nasogastric tube.
  • Storage requirements: The manufacturer product information should be consulted.
  • Reconstitution/preparation techniques: The manufacturer product information should be consulted.
  • IV compatibility: The manufacturer product information should be consulted.

General:
  • -This drug may be used concomitantly with antacids without affecting the absorption.
  • -Reflux symptoms may take 2 to 3 days to improve after initiation.
  • -Rapid acid control may be achieved within an hour at an IV dose of 160 mg.
Monitoring:
  • -Magnesium levels, especially in patients taking other drugs that could result in hypomagnesemia or those on long-term therapy
  • -Vitamin B12 levels, especially in patients on long-term therapy
  • -Bone fractures, especially in patients at high-risk for osteoporosis-related events
  • -Liver function tests, especially in patients with impaired liver function
  • -Renal function tests

Patient advice:
  • -Advise patients to avoid taking concomitant proton pump inhibitors and/or H2 antagonists during treatment.
  • -If using this drug to treat H pylori, tell patients that it is important to complete the full regimen.
  • -Instruct patients to seek medical attention if signs/symptoms of hypersensitivity, Clostridium difficile, or systemic cutaneous lupus erythematosus occur.
  • -Patients should be told that treatment may not provide immediate relief and that they should not take this drug for prophylaxis. Symptomatic relief may occur after 1 day of treatment, but patients should continue treatment for the full duration to achieve complete symptom control.
  • -Inform patients that this drug may cause dizziness or blurred vision, and they should avoid driving or operating machinery if these side effects occur.
  • -Advise patients to speak to their healthcare provider if they become pregnant, intend to become pregnant, or are breastfeeding.
Further information

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use pantoprazole only for the indication prescribed.
Trade Information
  • Payment Terms
  • Cash in Advance (CID), Cash on Delivery (COD), Cash Against Delivery (CAD)
  • Supply Ability
  • AS PER MARKET DEMANDS Per Day
  • Delivery Time
  • 45 Days
  • Sample Available
  • Yes
  • Sample Policy
  • Within a certain price range free samples are available
  • Packaging Details
  • 1*10*10
  • Main Domestic Market
  • All India
  • Certifications
  • Drug Licence, WHO GMP Certified, FSSAI, USFDA Approved

MEDILON HEALTHCARE
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MEDILON HEALTHCARE
"A Pharmaceutical Manufacturing Company"
C&F (nickon Pharma) 1a-Second Floor, Dawa Bazar, Indore - 452001, Madhya Pradesh, India
Phone :+918068344891
Mr Krishan Yadav (Manager)
Mobile :+918068344891

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Administration Office:
H.No-561, Near Qila, Manimajra, Chandigarh -160101

Registered Office:
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